Sheffield Bioinformatics Core has been working with Dr. Thushan de Silva and his group from the Department of Infection, Immunity and Cardiovascular Disease in the university to deliver SARS-CoV-2 sequencing, as part of the COVID-19 Genomics UK (COG-UK) project. The Sheffield COVID-19 Genomics Group sequence SARS-CoV-2 positive samples from hospitals and health-care facilities throughout Yorkshire and The Humber to ensure the local NHS trusts and public health teams are delivered timely information on the lineage composition of the viruses circulating in the local community.
In early May, the team identified a cluster of novel SARS-CoV-2 viruses, with a constellation of concerning spike gene mutations. This virus cluster is now designated AV.1 and was made the variant under investigation (VUI-21MAY-01) by Public Health England. It’s circulation in the UK is being closely monitored.
For queries relating to collaborating with the Bioinformatics Core team on projects: bioinformatics-core@sheffield.ac.uk
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Requests for a Bioinformatics support clinic can be made via the Research Software Engineering (RSE) code clinic system. This is monitored by Bioinformatics Core staff, so we will ensure the appropriate expertise (which may involve individuals from multiple teams) will be available to help you
Queries regarding sequencing and library preparation provision at The University of Sheffield should be directed to the Multi-omics facility in SITraN or the Genomics Laboratory in Biosciences.
